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br Experimental Procedures br Author Contributions br Acknow
2019-09-16
Experimental Procedures Author Contributions Acknowledgments Research in the Davis laboratory was supported by grants 4R37NS019904, 5R01NS052351, and 1R35NS097224 from NINDS. Research in the Martemyanov laboratory was supported by grants DA036596 and DA026405 from NIDA, and MH105482 from NI
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Moreover maintaining the pyrimidine pool is not
2019-09-16
Moreover, maintaining the pyrimidine pool is not the only important role played by DHODHs. In Toxoplasma gondii, for instance, DHODH plays a second essential function [38] possibly coupled to the mitochondrial respiratory activity, where it replenishes ubiquinol levels and prevents reactive oxygen s
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Proteins that associate to PCNA are characterized by having
2019-09-16
Proteins that associate to PCNA are characterized by having conserved motifs as the PCNA-interacting protein (PIP) motif [29,30], its variant PIP-like motif [31,32] or the APIM motif (Alk B homologue 2 PCNA interacting motif [33,34]); for instance, p21 contains a PIP motif [30], and DNA polymerases
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ERR is constitutively active in the
2019-09-12
ERRγ is constitutively active in the absence of endogenous ligand. However, several synthetic ligands that can repress or induce ERRγ function by disrupting ERRγ-coactivator interactions have been reported to date.
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The present study has shown
2019-09-11
The present study has shown that additional protein stability can be achieved (Fig. 6).
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In the horse oviduct the EP receptor was most strongly
2019-09-10
In the horse oviduct, the EP2 receptor was most strongly expressed in epithelial LiCl particularly in nonciliated (secretory) epithelial cells as evidenced by IHC.
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However the Moon is not the only possible source for
2019-09-09
However, the Moon is not the only possible source for space resources.
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Although CCR expression clearly identifies MBC precursors
2019-09-07
Although CCR6 expression clearly identifies MBC precursors within the GC, we found that the expression of this chemokine receptor by responding GNF 5 was not required for MBC differentiation and had no detectable impact on the GC subsets analyzed in this study.
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In astrocytes mitogen activated protein kinases MAPKs
2019-09-06
In astrocytes, mitogen-activated protein kinases (MAPKs) are activated after OGD-induced ischemic injury (Yung and Tolkovsky, 2003, Niu et al., 2009) and they regulate induction of AQP expression (Arima et al., 2003, McCoy and Sontheimer, 2010).
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br Introduction Rhabdomyosarcoma RMS is a myogenic tumor tha
2019-09-05
Introduction Rhabdomyosarcoma (RMS) is a myogenic tumor that accounts for approximately 50% of all pediatric soft tissue sarcomas.
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The data regarding the association
2019-09-04
The data regarding the association between COMT Val158/108Met and cognitive function are divergent [10,11,12,22,24,25,26,27,28].
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The reaction of chitosan with DVS
2019-09-03
The reaction of chitosan with DVS should take place primarily through a nucleophilic attack of the vinyl sulfone groups to the amino groups in chitosan [39,50], although its hydroxyl groups can also be involved, as it happens when using agarose [35].
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br DDR receptor and MMP expression Type II collagen
2019-09-02
DDR2 receptor and MMP-13 expression Type II collagen protein in articular cartilage is highly stable structure as its half-life is 117 years [43].
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CU CPT 4a In recent years there has been a dramatic increase
2019-08-30
In recent years there has been a dramatic increase in identification and optimization of potent CRTh2 antagonists which may not only inhibit the recruitment and activation of Th2 cells but also accelerate apoptosis and clearance of these cells from inflamed tissue, thereby promoting the resolution of allergic inflammation [7].
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The elastase induced injury model has been shown to
2019-08-29
The elastase-induced injury model has been shown to produce airspace enlargement, and increases in lung volume and compliance that are similar to those observed in human patients (Hantos et al., 2008, Hamakawa et al., 2011).
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