• Among our patients with anti enolase drusen those with a

  2019-09-16

  

  Among our patients with anti-enolase drusen, those with a relatively short duration from the onset of visual symptoms to the first visit tended to have normal structure of photoreceptors with preserved visual function, despite the presence of drusen-related RPE abnormalities (Cases 1-3 and 8). In co

• br Results br Discussion CCA is a fatal tumor originating

  2019-09-16

  

  Results Discussion CCA is a fatal tumor originating from the intrahepatic bile duct and the prognosis is very poor (Hoyos et al., 2018). CCA is one of the most dangerous primary liver malignant tumors and the most common malignant tumor of the biliary tract worldwide. However, the underlying m

• br Significance Dysregulation of dopamine homeostasis contri

  2019-09-16

  

  Significance Dysregulation of dopamine homeostasis contributes to Parkinson\'s disease (PD). The nuclear receptor Nurr1 plays a central role in dopamine homeostasis, regulating the transcription of (R)-(-)-Niguldipine hydrochloride clinical governing the synthesis, packaging, and reuptake of dop

• br Experimental Procedures br Author Contributions br Acknow

  2019-09-16

  

  Experimental Procedures Author Contributions Acknowledgments Research in the Davis laboratory was supported by grants 4R37NS019904, 5R01NS052351, and 1R35NS097224 from NINDS. Research in the Martemyanov laboratory was supported by grants DA036596 and DA026405 from NIDA, and MH105482 from NI

• Moreover maintaining the pyrimidine pool is not

  2019-09-16

  

  Moreover, maintaining the pyrimidine pool is not the only important role played by DHODHs. In Toxoplasma gondii, for instance, DHODH plays a second essential function [38] possibly coupled to the mitochondrial respiratory activity, where it replenishes ubiquinol levels and prevents reactive oxygen s

• Proteins that associate to PCNA are characterized by having

  2019-09-16

  

  Proteins that associate to PCNA are characterized by having conserved motifs as the PCNA-interacting protein (PIP) motif [29,30], its variant PIP-like motif [31,32] or the APIM motif (Alk B homologue 2 PCNA interacting motif [33,34]); for instance, p21 contains a PIP motif [30], and DNA polymerases

• ERR is constitutively active in the

  2019-09-12

  ERRγ is constitutively active in the absence of endogenous ligand. However, several synthetic ligands that can repress or induce ERRγ function by disrupting ERRγ-coactivator interactions have been reported to date.

• The present study has shown

  2019-09-11

  The present study has shown that additional protein stability can be achieved (Fig. 6).

• In the horse oviduct the EP receptor was most strongly

  2019-09-10

  In the horse oviduct, the EP2 receptor was most strongly expressed in epithelial LiCl particularly in nonciliated (secretory) epithelial cells as evidenced by IHC.

• However the Moon is not the only possible source for

  2019-09-09

  However, the Moon is not the only possible source for space resources.

• Although CCR expression clearly identifies MBC precursors

  2019-09-07

  Although CCR6 expression clearly identifies MBC precursors within the GC, we found that the expression of this chemokine receptor by responding GNF 5 was not required for MBC differentiation and had no detectable impact on the GC subsets analyzed in this study.

• In astrocytes mitogen activated protein kinases MAPKs

  2019-09-06

  In astrocytes, mitogen-activated protein kinases (MAPKs) are activated after OGD-induced ischemic injury (Yung and Tolkovsky, 2003, Niu et al., 2009) and they regulate induction of AQP expression (Arima et al., 2003, McCoy and Sontheimer, 2010).

• br Introduction Rhabdomyosarcoma RMS is a myogenic tumor tha

  2019-09-05

  Introduction Rhabdomyosarcoma (RMS) is a myogenic tumor that accounts for approximately 50% of all pediatric soft tissue sarcomas.

• The data regarding the association

  2019-09-04

  The data regarding the association between COMT Val158/108Met and cognitive function are divergent [10,11,12,22,24,25,26,27,28].

• The reaction of chitosan with DVS

  2019-09-03

  The reaction of chitosan with DVS should take place primarily through a nucleophilic attack of the vinyl sulfone groups to the amino groups in chitosan [39,50], although its hydroxyl groups can also be involved, as it happens when using agarose [35].

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