• Although intact Chk is distributed throughout the

  2020-08-14

  

  Although intact Chk is distributed throughout the nucleus and the cytoplasm (Fig. 1), the deletion of the SH2 domain greatly augments nuclear localization of Chk. The SH2 domain-deleted mutants might lose the ability to localize to the exterior of the nucleus due to a lack of the binding to a hypoth

• E3330 br Membrane receptor Indirect non genomic signaling As

  2020-08-14

  

  Membrane receptor: Indirect non-genomic signaling As mentioned above, not all E3330 responses fit the classical genomic model of steroid action. The observation of excessively fast estrogen-induced biological responses led to the development of the hypothesis that estrogen could be acting by mec

• In different body organs a number of biological functions

  2020-08-13

  

  In different body organs, a number of biological functions are generally mediated by binding of the extracellular substances to the particular transmembrane receptors, which results in subsequent signal stimulation by intracellular signaling cascades. These cascades function over the complex network

• br Materials and methods br

  2020-08-13

  

  Materials and methods Result and discussion qRT-PCR was utilized to explore the effect of acetamizuril on the mRNA level of enolase. The results were analyzed according to the Livak 2−ΔΔCT method (Schmittgen and Livak, 2008): the mean CT of the enolase in treated and untreated samples was 29.8

• In principle in vitro techniques for

  2020-08-13

  

  In principle, in vitro techniques for assessing enzyme induction might include the use of cultured hepatocytes, precision-cut liver slices, immortalized Lapatinib australia lines (such as those derived from hepatomas) and reporter gene constructs (where appropriate cells are transfected with recomb

• Introduction The number of patients with type diabetes is

  2020-08-13

  

  Introduction The number of patients with type 2 diabetes is increasing globally, and has become a serious public health problem. Type 2 diabetic patients exhibit a higher risk of bone fracture [1]. In addition, clinical studies have indicated that increased fracture risk is associated with long-ter

• Another important issue in biosensors is to design

  2020-08-13

  

  Another important issue in biosensors is to design a simple and potable detection strategy to meet the requirement of the point-of-care (POC) test applications. According to the recent research, by using invertase fluvastatin for hydrolyzing sucrose into glucose, the range of personal glucometer ha

• br Materials and methods br Results The

  2020-08-13

  

  Materials and methods Results The BUN and creatinine levels in the saline-treated CRF group were found to be significantly higher than those in the sham-operated control rats treated with either montelukast or saline (pand NS 1619 mg tissues, were found to be significantly higher in the salin

• In S hexyl GSH non treated guinea pigs antigen

  2020-08-13

  

  In S-hexyl GSH non-treated guinea pigs, antigen-induced anaphylactic response was suppressed by montelukast, but not by BayCysLT2RA, indicating that this asthmatic response was basically CysLT1-receptor-dependent. On the other hand, the suppressive effect of montelukast was weakened by treatment wit

• br Materials and methods br Results br Discussion

  2020-08-13

  

  Materials and methods Results Discussion In this study, we have shown that fat body-specific knockdown of the key splicing factors U1-70K and U2AF lead to decreased triglyceride storage phenotypes in larvae. Additionally, there was no accompanying defect in glycogen storage observed in thes

• br Selection of ions for GaN Systems

  2020-08-13

  

  Selection of ions for GaN Systems sample test Sample construction analyses has been provided to analyze the beam penetration of several ions of the cocktail in the component. An X-ray and optical view of GaN System devices parts is presented at Fig. 5, Fig. 6 respectively. The drain and source el

• An increased CK activity was found in septal

  2020-08-12

  

  An increased CK2 activity was found in septal neuronal Cy7 carboxylic acid (non-sulfonated) dissected from rat embryos after hypoglycemia [36]. These data indicated that CK2 activity is not only regulated by insulin but also by the glucose concentration. One essential step in insulin action is the

• Previous and ongoing clinical trials

  2020-08-11

  

  Previous and ongoing clinical trials have been summarized in a recent review (Siaw-Debrah et al., 2017). To our knowledge, there are no ongoing or completed clinical trials focusing on cytokines in ICH. Published studies have focused mainly on cytokine changes in ICH patients (summarized in Table 3)

• As we all known hypoxia is

  2020-08-11

  

  As we all known, hypoxia is a hallmark of tumour microenvironment, which is a key regulator of tumour growth and metastasis [4]. Hypoxia meditates a series of cellular responses including angiogenesis by activating transcriptional factor hypoxia inducible factor (HIF), which is consist of an obligat

• br User knowledge representation Various representation appr

  2020-08-11

  

  User knowledge representation Various representation approaches of user interests and preferences are proposed. In this work, we advocate a multidimensional semantic approach based on Bouzghoub et al. meta-model (Bouzeghoub and Kostadinov, 2005), depicted in Fig. 6, to model the user profile. The

13602 records 737/907 page Previous Next First page 上5页 736737738739740 下5页 Last page